The 49ers and wide receiver Brandon Aiyuk got the worst news on his injured right knee. According to a report from Fox Sports ...

The San Francisco 49ers have fallen well out of the 'Super Bowl contender' range in the USA TODAY NFL power rankings.

With the Los Angeles Rams season heading towards the pit of despair, many have speculated about the availability of star ...

This week’s 49ers mailbag is stocked with questions (and answers) regarding their offensive shortcomings, fourth-quarter ...

Drake London and Tyler Lockett are among UPI senior sports writer Alex Butler's four must-start wide receivers for Week 8 of ...

The San Francisco 49ers just lost star receiver Brandon Aiyuk for the season because of a devastating knee injury, leaving ...

On Monday, San Francisco 49ers wide receiver Deebo Samuel expressed his support for his injured teammate, Brandon Aiyuk. Head ...

San Francisco 49ers wide receiver Brandon Aiyuk (11) is hit by Kansas City Chiefs cornerback Trent McDuffie, left, and safety ...

Tua Tagovailoa and Romeo Doubs lead UPI senior sports writer Alex Butler's fantasy football waiver wire priority list for ...

Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

The 49ers are among the Top-15 stop units in most advanced metrics, including sitting seventh in defensive DVOA at FTN. San ...

Tampa wide receiver Chris Godwin reportedly dislocated his ankle against the Ravens on Monday night, and the injury was so ...