The 49ers have been on the wrong side of the rest differential by historical proportions in each of their last two schedules.

The 49ers struck gold in Round 3 of the NFL Draft this year. They took Dominick Puni, who played every position on the ...

Juszczyk has created custom NFL designs for stars like Taylor Swift, Simone Biles and Olivia Culpo. But her latest client may ...

The Oct. 20 matchup between the San Francisco 49ers (3-3) and Kansas City Chiefs (5-0) features a standoff at the QB position ...

San Francisco spent the week answering questions about a slow start to the season before sending its strongest message to ...

The 49ers beat a middling Seahawks team to improve their record to 3-3. Here are five things we learned about the 49ers in ...

San Francisco 49ers cornerback Deommodore Lenoir is feeling good after shutting down Seattle Seahawks wide receiver DK ...

San Francisco 49ers head coach Kyle Shanahan confirmed Friday in a conference call that running back Jordan Mason avoided a ...

A seemingly safe 20-point lead for San Francisco had been cut to six points by Seattle and the 49ers appeared to be on the ...

Niners rookie WR Ricky Pearsall is set to return to practice next week for the first time since he was shot in the chest in ...

Guerendo's big play has created quite the debate in the 49ers locker room. The rookie running back claims he was told to ...

San Francisco 49ers head coach Kyle Shanahan provided yet another unfortunate injury update on star running back Christian ...