The Week 7 NFL schedule is arguably the most loaded of the year, highlighted by a Super Bowl rematch of Chiefs vs. 49ers at 4:25 p.m. ET on Sunday. Kansas City is a 1.5-point road underdog, per the latest Week 7 NFL odds,

The 49ers have had several extra days of rest themselves — a condition in which Brock Purdy is 3-0 straight up in regular-season games when the spread is four points or less. The Chiefs’ league-leading pressure rate is challenged with Purdy’s 67 percent completion rate when under duress.

The Los Angeles Chargers (3-2) are favored by just 1.5 points against the Arizona Cardinals (2-4) on Monday, October 21, 2024.NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 10:58