Many drugs show “polypharmacology,” meaning they clearly affect distinct targets. These 'off-target' profiles can be very different despite similarities in chemical structure, which is not as ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

A new review has highlighted how skin tone can affect the safety and effectiveness of some medications and why the current ...

A marketed drug has three names: a chemical name, a generic name, and a brand name. A chemical name is given when a new chemical entity (NCE) is developed. The chemical name is a scientific name ...

Min Son of Hanol IP & Law reports on a decision that should provide improved guidance in determining whether patents or ...

Researchers developed SmartCADD, a tool using AI, quantum mechanics, and Computer-Assisted Drug Design (CADD) to accelerate ...

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can ...

Ingestion of doses as small as 0.25mg can be fatal," states the US Drug Enforcement Agency (DEA). Getty Images It's also relatively easy to alter its chemical structure to produce similar ...

Drug discovery has traditionally been slow and expensive, often taking decades and costing manufacturers billions. But with ...

Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era ...

Wu Xiaohui of Wanhuida Intellectual Property explains why a recent decision on inventiveness assessments of co-solvent ...

In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers.